Criação de questionário e modelo de rastreamento de lipedema
Development of a questionnaire and screening model for lipedema
Alexandre Campos Moraes Amato; Fernando Campos Moraes Amato; Daniel Augusto Benitti; Lorena Guimarães Lima Amato
Background: Lipedema is greatly underdiagnosed and there is a lack of low-cost tools to facilitate diagnostic. We created a lipedema screening questionnaire based on a questionnaire for assessing symptoms. Objectives: The study objectives were to identify relevant clinical questions, develop a screening questionnaire, and construct a model for predicting lipedema. Method: A simplified questionnaire was constructed and administered to a sample of patients with and without lipedema and then the probability of correct diagnosis was analyzed. Results: All 109 patients who answered the questionnaire were female and all of them understood the questions. A predictive model using individual question scores achieved an excellent probability of correct diagnosis, at 91.2%, and a predictive model based on total score also achieved a good probability of correct diagnosis, at 86.15%. Conclusions: The lipedema screening questionnaire is a practical instrument that is quick and easy to administer and can be used with our population for identification of possible lipedema patients, raising the level of suspicion when taking a patient’s history and conducting a physical examination.
1 Moraes IN. Cânones da beleza. Rev Cult e Saude. 2003;1:25-30.
2 Amato ACM. Is Lipedema a Unique Entity? EC Clin Med Cases Reports. 2020;2:1-7.
3 Chen S-G, Hsu S-D, Chen T-M, Wang HJ. Painful fat syndrome in a male patient. Br J Plast Surg. 2004;57(3):282-6.
4 Ma W, Rockson SG, Oliver G. Platelet factor 4 is a biomarker for lymphatic-promoted disorders. JCI Insight. 2020;5(13):e135109.
5 Fife CE, Maus EA, Carter MJ. Lipedema: a frequently misdiagnosed and misunderstood fatty deposition syndrome. Adv Skin Wound Care. 2010;23(2):81-4.
6 Beninson J, Edelglass JW. Lipedema - the non-lymphatic masquerader. Angiology. 1984;35(8):506-10.
7 Campos A, Amato M, Vofchuk D, et al. Lipedema associado a obesidade, linfedema e insuficiência venosa: relato de um caso. Diagnóstico e Trat. 2020;25:4-8.
8 Reich-Schupke S, Altmeyer P, Stücker M. Thick legs - not always lipedema. J Dtsch Dermatol Ges. 2013;11(3):225-33. PMid:23231593.
9 Forner-Cordero I, Szolnoky G, Forner-Cordero A, Kemény L. Lipedema: an overview of its clinical manifestations, diagnosis and treatment of the disproportional fatty deposition syndrome - systematic review. Clin Obes. 2012;2(3-4):86-95.
10 Rapprich S, Dingler A, Podda M. Liposuktion ist eine wirksame Therapie beim Lipödem - Ergebnisse einer Untersuchung mit 25 Patientinnen. J Ger Soc Dermatology 2011; 9: 33-41.
11 Amato ACM, Amato FCM, Benitti DA, et al. Tradução adaptação cultural e validação do questionário de avaliação sintomática do lipedema (QuASiL). J Vasc Bras. 2020 [citado 2020 set 30];19:e20200049.
12 Augustin M, Bross F, Földi E, Vanscheidt W, Zschocke I. Development, validation and clinical use of the FLQA-l, a disease-specific quality of life questionnaire for patients with lymphedema. Vasa. 2005;34(1):31-5.
13 Dayan E, Kim JN, Smith ML, et al. Lipedema - The disease they call FAT: An overview for clinicians. Boston, MA: Lipedema Simplified Publications, The Friedman Center for Lymphedema Research and Treatment at The Center.
14 Child AH, Gordon KD, Sharpe P, et al. Lipedema: an inherited condition. Am J Med Genet A. 2010;152A(4):970-6.
15 Mandrekar JN. Receiver operating characteristic curve in diagnostic test assessment. J Thorac Oncol. 2010;5(9):1315-6.