A rare arteriovenous communication between left testicular vein with left accessory renal artery and multiple renal vascular anomalies: understanding the genetic and embryological perspective

Sarah S. Sangma; Neerja Rani; Jessy JP; Rajesh Kumar

doi:10.1590/1677-5449.202501252

Case Report

A rare arteriovenous communication between left testicular vein with left accessory renal artery and multiple renal vascular anomalies: understanding the genetic and embryological perspective

Uma comunicação arteriovenosa rara entre a veia testicular esquerda com a artéria renal esquerda acessória e a anatomia vascular renal múltipla: compreendendo a perspectiva genética e embriológica

Sarah S. Sangma; Neerja Rani; Jessy JP; Rajesh Kumar

http://dx.doi.org/10.1590/1677-5449.202501252 J Vasc Bras, vol.25, e20250125, 2025

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Abstract

Vascular malformations are abnormalities of the vascular tree, either congenital or acquired, which may involve arteries, veins, capillaries, or lymphatic vessels. Congenital malformations, such as patent ductus arteriosus, may persist into adulthood, resulting in abnormal vascular communications. Acquired vascular communications may occur following trauma, such as gunshot or stab injuries, or after surgical procedures. Arteriovenous malformations are congenital disorders affecting the circulatory system during early developmental stages. Renal vascular variations are also relatively common, usually silent (asymptomatic) and often diagnosed incidentally during surgical or radiological procedures. Renal artery variations occur in approximately 30% of the population. Renal vein variations are also frequent but are always overlooked than their arterial counterpart. In this case study, we report an abnormal communication along with multiple urogenital vascular anomalies and discuss their genetic and developmental perspectives. Recognition of such anomalies helps establish safety guidelines for the diagnosis and management of renal and gonadal disorders.

Keywords

abnormal arteriovenous communications; varicocele; accessory renal veins; accessory renal artery; renal transplantations

Resumo

Malformações vasculares são anomalias da árvore vascular que podem afetar artérias, veias, capilares ou vasos linfáticos, podendo ser congênitas e adquiridas. Malformações congênitas, como persistência do canal arterial, podem persistir em adultos, causando comunicações vasculares anormais. Comunicações adquiridas ocorrem após qualquer trauma, como ferimentos por arma de fogo ou facadas, e qualquer procedimento cirúrgico. Malformações arteriovenosas são doenças congênitas que afetam o sistema circulatório durante período inicial de desenvolvimento. Variações vasculares renais também não são incomuns e geralmente são silenciosas e assintomáticas, diagnosticadas incidentalmente durante procedimentos cirúrgicos e radiológicos. Variações da artéria renal ocorrem em 30% da população. Variações da veia renal também são bastante comuns, mas são sempre negligenciadas em comparação às suas contrapartes. Neste estudo, relatamos comunicação anormal e uma série de anomalias da vasculatura urogenital, sua perspectiva genética e de desenvolvimento. Tal anomalia fornecerá diretrizes de segurança para o diagnóstico e tratamento de distúrbios renais e gonadais.

Palavras-chave

comunicações arteriovenosas anormais; varicocele; veias renais acessórias; artéria renal acessória; transplantes renais

References

1 Standring S. Gray’s anatomy: the anatomical basis of clinical practice. 41st edition. New York: Elsevier; 2016. p. 1243-45.

2 Patel R, Nicholson AA. Arteriovenous fistula: etiology and treatment. Endovasc Today. 2012;11:45-51.

3 Thakur A, Loh HK, Mehta V, Suri RK, Rath G. Multiple bilateral variations in urogenital vasculature: a clinico-embryological perspective. J Morphol Sci. 2014;31:1-5.

4 Zhu J, Zhang L, Yang Z, Zhou H, Tang G. Classification of the renal vein variations: a study with multidetector computed tomography. Surg Radiol Anat. 2015;37(6):667-75. https://doi.org/10.1007/s00276-014-1403-6. PMid:25567101.

5 Hostiuc S, Rusu MC, Negoi I, Dorobanțu B, Grigoriu M. Anatomical variants of renal veins: a meta-analysis of prevalence. Sci Rep. 2019;9(1):10802. https://doi.org/10.1038/s41598-019-47280-8. PMid:31346244.

6 Gulas E, Wysiadecki G, Szymański J, et al. Morphological and clinical aspects of the occurrence of accessory (multiple) renal arteries. Arch Med Sci. 2018;14(2):442-53. https://doi.org/10.5114/aoms.2015.55203. PMid:29593819.

7 Yufa A, Mikael A, Lara G, Nurick H, Andacheh I. Accessory renal arteries involved in atherosclerotic occlusive disease at the aortic bifurcation. J Vasc Surg Cases Innov Tech. 2020;6(3):425-9. https://doi.org/10.1016/j.jvscit.2020.06.003. PMid:33367190.

8 Holman E. Abnormal arteriovenous communications great variability of effects with particular reference to delayed development of cardiac failure. Circulation. 1965;32(6):1001-9. https://doi.org/10.1161/01.CIR.32.6.1001. PMid:5846098.

9 Thomas JM, Surendran S, Abraham M, Rajavelu A, Kartha CC. Genetic and epigenetic mechanisms in the development of arteriovenous malformations in the brain. Clin Epigenetics. 2016;8(1):78. https://doi.org/10.1186/s13148-016-0248-8. PMid:27453762.

10 Kumar N, Swamy R, Patil J, Guru A, Aithal A, Shetty P. Presence of arteriovenous communication between left testicular vessels and its clinical significance. Case Rep Vasc Med. 2014;2014:160824. https://doi.org/10.1155/2014/160824. PMid:24716087.

11 Nayak BS, Rao KM, Shetty SD, Sirasanagandla SR, Kumar N, Guru A. Terminal bifurcation of the right testicular vein and left testicular arterio-venous anastomosis. Kathmandu Univ Med J. 2013;11(42):168-70. PMid:24096228.

12 Anjamrooz SH, Azari H, Abedinzadeh M. Abnormal patterns of renal veins. Anat Cell Biol. 2012;45(1):57-61. https://doi.org/10.5115/acb.2012.45.1.57. PMid:22536553.

13 Karadeniz GA, Korkmaz HAA, Çavuşoğlu İG. A very rare renal venous anomaly: accessory polar left renal vein. Turk Gogus Kalp Damar Cerrahisi Derg. 2019;27(2):241-4. https://doi.org/10.5606/tgkdc.dergisi.2019.17612. PMid:32082861.

14 Nayak SB, Pamidi N, Packirisamy V, Vasudeva SK. Multiple renal veins clogging the hilum of the right kidney. Anat Cell Biol. 2023;56(1):141-4. https://doi.org/10.5115/acb.22.109. PMid:36263505.

15 Cavoli GL, Matranga S, Amato A, et al. The renal transplant with multiple renal arteries graft. Saudi J Kidney Dis Transpl. 2022;33(12, Suppl 2):S100-1. https://doi.org/10.4103/1319-2442.374376. PMid:37102531.

Submitted date:
08/23/2025

Accepted date:
12/24/2025

Sociedade Brasileira de Angiologia e Cirurgia Vascular (SBACV)"> Sociedade Brasileira de Angiologia e Cirurgia Vascular (SBACV)">

A rare arteriovenous communication between left testicular vein with left accessory renal artery and multiple renal vascular anomalies: understanding the genetic and embryological perspective

Uma comunicação arteriovenosa rara entre a veia testicular esquerda com a artéria renal esquerda acessória e a anatomia vascular renal múltipla: compreendendo a perspectiva genética e embriológica

Sarah S. Sangma; Neerja Rani; Jessy JP; Rajesh Kumar

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