Jornal Vascular Brasileiro
https://www.jvascbras.org/article/doi/10.1590/S1677-54492013000100006
Jornal Vascular Brasileiro
Review Article

Pioderma Gangrenoso: um Artigo de Revisão

Pyoderma Gangrenosum: a Review Article

Clóvis Luíz Konopka; Geórgia Andrade Padulla; Michele Purper Ortiz; Anderson Kahl Beck; Mariana Rechia Bitencourt; Diogo Chagas Dalcin

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Resumo

O pioderma gangrenoso (PG) é uma dermatose crônica com características peculiares e de etiologia desconhecida, muitas vezes de difícil diagnóstico. Manifesta-se através de lesões cutâneas ulceradas e dolorosas com evolução rápida e progressiva, mais comumente em membros inferiores. As ulcerações podem surgir espontaneamente ou depois de variados tipos de trauma. O período entre o início das lesões e o diagnóstico correto costuma ser prolongado. Não existe nenhum tratamento padronizado ou algoritmo simples para a escolha da terapia. Neste artigo, os autores fazem uma ampla revisão da literatura atual acerca da fisiopatologia, do diagnóstico e do tratamento desta patologia através de análise sistemática das referências bibliográficas atuais nas bases de dados PubMed, Scielo, Medline e Lilacs.

Palavras-chave

pioderma gangrenoso, úlcera cutânea, diagnóstico diferencial

Abstract

Pyoderma gangrenosum (PG) is a chronic dermatosis with peculiar characteristics and unknown etiology, often of difficult diagnosis. It manifests as painful skin ulcers with rapid and progressive evolution, most commonly in the lower limbs. Ulcerations can occur spontaneously or after various types of trauma. The period between the onset of the lesions and the correct diagnosis is often prolonged. There is no standard treatment or simple algorithm for the choice of therapy. In this article, we present a comprehensive review of the current literature on the pathophysiology, diagnosis, and treatment of this pathology through systematic analysis of the current references in the databases PubMed, Scielo, Medline and Lilacs.

Keywords

pyoderma gangrenosum, skin ulcer, differential diagnosis

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